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VOR BIOPHARMA

PIONEERING HEMATOPOIETIC STEM CELL (HSC) THERAPIES TO UNLEASH THE POTENTIAL OF TARGETED IMMUNOTHERAPIES FOR HEME MALIGNANCIES

ABOUT VOR

 

Vor Biopharma is pioneering hematopoietic stem cell (HSC) therapies to unleash the potential of targeted immunotherapies for heme malignancies. Vor HSCs are uniquely modified via gene editing technologies to expand the scope of targeted immunotherapies (such as CAR-T, bi-specific mAbs, ADCs, and others) against cancer targets not viable with the current approaches, and dramatically reduce treatment toxicities. Designed to replace conventional bone marrow transplantation, this strategy could lead to deep and lasting clinical remissions for a host of blood-borne cancers with poor prognoses. This technology platform is covered by broad IP exclusively licensed from Columbia University as well as internally filed patent applications. Vor Biopharma was co-founded by PureTech Health and Siddhartha Mukherjee, MD, DPhil of Columbia University, and is supported by a Scientific Advisory Board including Dan Littman, PhD (NYU), Derrick Rossi, PhD (HMS), Crystal Mackall, MD (Stanford), Sanjiv Sam Gambhir, MD, PhD (Stanford), Justin Stebbing, PhD, FRCP (Imperial College London), and Joseph Bolen, PhD (PureTech)

Our Team

Joseph Bolen, Ph.D.
Acting Chief Scientific Officer and Member of the Scientific Advisory Board

Dr. Bolen is also Chief Scientific Officer at PureTech Health. Dr. Bolen has more than 30 years of industry and research experience and has been at the forefront of cancer and immunology research. He began ...


Sanjiv Sam Gambhir, M.D., Ph.D.
Member of the scientific advisory board

Dr. Gambhir is a Professor of Radiology, Materials Science & Engineering, and Bioengineering at Stanford University, where he is also Chair of the Department of Radiology and Director of the Molecular Imaging Program. He is the recipient of over $90M in NIH ...


Dan Littman, M.D., Ph.D.
member of the scientific advisory board

Dr. Littman is a Howard Hughes Medical Institute Investigator and the Helen L. and Martin S. Kimmel Professor of Molecular Immunology and Professor of Pathology and Microbiology at the New York University (NYU) School of Medicine. Dr. Littman has made ...


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Siddhartha Mukherjee, M.D., D.Phil
Member of the Scientific Advisory Board

Dr. Mukherjee is an Assistant Professor of Medicine at Columbia University and a Staff Physician at Columbia University Medical Center. Dr. Mukherjee is the author of The Emperor of All Maladies: A Biography of Cancer, winner of the 2011 Pulitzer Prize in ...


Derrick J. Rossi, Ph.D.
member of the scientific advisory board

Dr. Rossi is an Associate Professor in the Stem Cell and Regenerative Biology Department at Harvard Medical School and Harvard University. Dr. Rossi is also an investigator in the Program in Cellular and Molecular Medicine at Boston Children’s ...


Justin Stebbing, Ph.D., F.R.C.P., F.R.C.Path.
Member of the Scientific Advisory Board

Dr. Stebbing is a Professor of Cancer Medicine and Oncology & Consultant Oncologist at Imperial College London and Imperial College Healthcare National Health Service (NHS) Trust. Dr. Stebbing’s research is focused on discovering new ...


David Steinberg
SENIOR ADVISOR

Mr. Steinberg has led the development of a number of programs, including Vedanta Biosciences, Entrega Biosciences, and Commense Health. He also served ...


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Aleks Radovic-Moreno, Ph.D.
 

Dr. Radovic-Moreno is Vice President at PureTech Health. He was previously a Research Scientist at the biotech startup AuraSense Therapeutics, where he was a lead inventor of the company's core immunotherapy platform. Dr. Radovic-Moreno completed ...

CAREERS

 

 

CONTACT US

 
 

VOR BIOPHARMA, INC
501 BOYLSTON STREET
SUITE 6102
BOSTON, MA 02116

 

EMAIL: info@vorbiopharma.com